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Earnings release · 8-K Exhibit 99

Johnson & Johnson · Earnings release · 8-K Exhibit 99

JNJ · Health Care

Filed 2026-01-21 · CY2026 Q1 · Company’s FY2026 Q1 · 5,511 words

Read the original on sec.gov ↗

Palanor summary

Johnson & Johnson reported Q4 2025 worldwide sales of $24.6B, up 9.1% (7.1% operational). Innovative Medicine grew 10.0% driven by oncology franchise (DARZALEX +26.6%, CARVYKTI +65.8%) and neuroscience additions including Caplyta acquisition. MedTech advanced 7.5% with cardiovascular strength (Shockwave +23.3%, ABIOMED +19.8%). STELARA faced biosimilar erosion (-47.7%). Adjusted EPS reached $2.46, up 20.6% year-over-year. The company completed orthopaedics restructuring in Q4 and continues surgery franchise optimization through 2026.

Written by Palanor from the full document. Not the company’s words.

Sentiment

+0.62

Confidence

71%

Scored on the whole document. No single passage carries these two numbers, so none is highlighted.

EX-99.23a2025q4exhibit992.htmEX-99.2 Document

Exhibit 99.2

Johnson & Johnson and subsidiaries

Supplementary sales data

(Unaudited; Dollars in Millions)

FOURTH QUARTER

Percent Change

Sales to customers by geographic area

2025

2024

Total

Operations

Currency

U.S.

$14,195

13,204

7.5

%

7.5

—

Europe

5,598

4,921

13.8

5.2

8.6

Western Hemisphere excluding U.S.

1,271

1,135

12.0

11.0

1.0

Asia-Pacific, Africa

3,500

3,260

7.4

7.2

0.2

International

10,369

9,316

11.3

6.6

4.7

Worldwide

$24,564

22,520

9.1

%

7.1

2.0

Note: Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

Johnson & Johnson and subsidiaries

Supplementary sales data

(Unaudited; Dollars in Millions)

TWELVE MONTHS

Percent Change

Sales to customers by geographic area

2025

2024

Total

Operations

Currency

U.S.

$53,752

50,302

6.9

%

6.9

—

Europe

21,535

20,212

6.5

2.4

4.1

Western Hemisphere excluding U.S.

4,875

4,714

3.4

8.4

(5.0)

Asia-Pacific, Africa

14,031

13,593

3.2

3.1

0.1

International

40,441

38,519

5.0

3.4

1.6

Worldwide

$94,193

88,821

6.0

%

5.3

0.7

Note: Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

Johnson & Johnson and subsidiaries

Supplementary sales data

(Unaudited; Dollars in Millions)

FOURTH QUARTER

Percent Change

Sales to customers by segment of business

2025

2024

Total

Operations

Currency

Innovative Medicine

U.S.

$

9,689

8,977

7.9

%

7.9

—

International

6,074

5,355

13.4

7.9

5.5

15,763

14,332

10.0

7.9

2.1

MedTech

U.S.

4,506

4,227

6.6

6.6

—

International

4,295

3,961

8.5

4.9

3.6

8,801

8,188

7.5

5.8

1.7

U.S.

14,195

13,204

7.5

7.5

—

International

10,369

9,316

11.3

6.6

4.7

Worldwide

$

24,564

22,520

9.1

%

7.1

2.0

Note: Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

Johnson & Johnson and subsidiaries

Supplementary sales data

(Unaudited; Dollars in Millions)

TWELVE MONTHS

Percent Change

Sales to customers by segment of business

2025

2024

Total

Operations

Currency

Innovative Medicine

U.S.

$

36,344

33,970

7.0

%

7.0

—

International

24,057

22,994

4.6

2.9

1.7

60,401

56,964

6.0

5.3

0.7

MedTech

U.S.

17,408

16,332

6.6

6.6

—

International

16,384

15,525

5.5

4.1

1.4

33,792

31,857

6.1

5.4

0.7

U.S.

53,752

50,302

6.9

6.9

—

International

40,441

38,519

5.0

3.4

1.6

Worldwide

$

94,193

88,821

6.0

%

5.3

0.7

Note: Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

Johnson & Johnson and subsidiaries

Condensed consolidated statement of earnings

(Unaudited; in Millions Except Per Share Figures)

FOURTH QUARTER

2025

2024

Percent

Increase

(Decrease)

Amount

Percent

to Sales

Amount

Percent

to Sales

Sales to customers

$

24,564

100.0

$

22,520

100.0

9.1

Cost of products sold

7,968

32.4

7,128

31.6

11.8

Gross Profit

16,596

67.6

15,392

68.4

7.8

Selling, marketing and administrative expenses

6,753

27.5

6,453

28.6

4.6

Research and development expense

4,252

17.3

5,298

23.5

(19.7)

In-process research and development impairments

81

0.3

17

0.1

Interest (income) expense, net

(23)

(0.1)

(144)

(0.6)

Other (income) expense, net

483

2.0

(161)

(0.7)

Restructuring

84

0.4

42

0.2

Earnings before provision for taxes on income

4,966

20.2

3,887

17.3

27.8

(Benefit from)/Provision for taxes on income

(150)

(0.6)

456

2.1

(132.9)

Net earnings

$

5,116

20.8

$

3,431

15.2

49.1

Net earnings per share (Diluted)

$

2.10

$

1.41

48.9

Average shares outstanding (Diluted)

2,439.0

2,427.1

Effective tax rate

(3.0)

%

11.7

%

Adjusted earnings before provision for taxes and net earnings (1) (A)

Earnings before provision for taxes on income

$

7,046

28.7

$

5,421

24.1

30.0

Net earnings

$

6,009

24.5

$

4,946

22.0

21.5

Net earnings per share (Diluted)

$

2.46

$

2.04

20.6

Effective tax rate

14.7

%

8.8

%

(1) See Reconciliation of Non-GAAP Financial Measures.

(A) NON-GAAP FINANCIAL MEASURES "Adjusted earnings before provision for taxes on income," "adjusted net earnings," "adjusted net earnings per share (diluted)," and "adjusted effective tax rate" are non-GAAP financial measures and should not be considered replacements for GAAP results. The Company provides earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate on an adjusted basis because management believes that these measures provide useful information to investors. Among other things, these measures may assist investors in evaluating the Company's results of operations period over period. In various periods, these measures may exclude such items as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters).

Special items may be highly variable, difficult to predict, and of a size that sometimes has substantial impact on the Company's reported results of operations for a period. Management uses these measures internally for planning, forecasting and evaluating the performances of the Company's businesses, including allocating resources and evaluating results relative to employee performance compensation targets. Unlike earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate prepared in accordance with GAAP, adjusted earnings before provision for taxes on income, adjusted net earnings, adjusted net earnings per share (diluted), and adjusted effective tax rate may not be comparable with the calculation of similar measures for other companies.

The limitations of using these non-GAAP financial measures as performance measures are that they provide a view of the Company's results of operations without including all events during a period, such as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters) and do not provide a comparable view of the Company's performance to other companies in the health care industry. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP.

Johnson & Johnson and subsidiaries

Condensed consolidated statement of earnings

(Unaudited; in Millions Except Per Share Figures)

TWELVE MONTHS

2025

2024

Percent

Increase

(Decrease)

Amount

Percent

to Sales

Amount

Percent

to Sales

Sales to customers

$

94,193

100.0

$

88,821

100.0

6.0

Cost of products sold

30,256

32.1

27,471

30.9

10.1

Gross Profit

63,937

67.9

61,350

69.1

4.2

Selling, marketing and administrative expenses

23,676

25.1

22,869

25.7

3.5

Research and development expense

14,665

15.6

17,232

19.4

(14.9)

In-process research and development impairments

81

0.1

211

0.2

Interest (income) expense, net

(85)

(0.1)

(577)

(0.6)

Other (income) expense, net

(7,209)

(7.6)

4,694

5.3

Restructuring

228

0.2

234

0.3

Earnings before provision for taxes on income

32,581

34.6

16,687

18.8

95.2

Provision for taxes on income

5,777

6.1

2,621

3.0

120.4

Net earnings

$

26,804

28.5

$

14,066

15.8

90.6

Net earnings per share (Diluted)

$

11.03

$

5.79

90.5

Average shares outstanding (Diluted)

2,429.4

2,429.4

Effective tax rate

17.7

%

15.7

%

Adjusted earnings before provision for taxes and net earnings (1) (A)

Earnings before provision for taxes on income

$

31,681

33.6

$

28,979

32.6

9.3

Net earnings

$

26,215

27.8

$

24,242

27.3

8.1

Net earnings per share (Diluted)

$

10.79

$

9.98

8.1

Effective tax rate

17.3

%

16.3

%

(1) See Reconciliation of Non-GAAP Financial Measures.

(A) NON-GAAP FINANCIAL MEASURES "Adjusted earnings before provision for taxes on income," "adjusted net earnings," "adjusted net earnings per share (diluted)," and "adjusted effective tax rate" are non-GAAP financial measures and should not be considered replacements for GAAP results. The Company provides earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate on an adjusted basis because management believes that these measures provide useful information to investors. Among other things, these measures may assist investors in evaluating the Company's results of operations period over period. In various periods, these measures may exclude such items as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters).

Special items may be highly variable, difficult to predict, and of a size that sometimes has substantial impact on the Company's reported results of operations for a period. Management uses these measures internally for planning, forecasting and evaluating the performances of the Company's businesses, including allocating resources and evaluating results relative to employee performance compensation targets. Unlike earnings before provision for taxes on income, net earnings, net earnings per share (diluted), and effective tax rate prepared in accordance with GAAP, adjusted earnings before provision for taxes on income, adjusted net earnings, adjusted net earnings per share (diluted), and adjusted effective tax rate may not be comparable with the calculation of similar measures for other companies.

The limitations of using these non-GAAP financial measures as performance measures are that they provide a view of the Company's results of operations without including all events during a period, such as intangible asset amortization expense, significant gains from divestitures, the effects of an acquisition, restructuring, litigation, and changes in applicable laws and regulations (including significant accounting or tax matters) and do not provide a comparable view of the Company's performance to other companies in the health care industry. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP.

Johnson & Johnson and subsidiaries

Reconciliation of non-GAAP financial measures

Fourth Quarter

(Dollars in Millions Except Per Share Data)

2025

2024

Net Earnings, after tax- as reported

$5,116

$3,431

Pre-tax Adjustments

Litigation related

854

(16)

Intangible Asset Amortization expense

1,186

1,171

Restructuring related 1

210

62

Acquisition, integration and divestiture related

(190)

298

IPR&D impairments

81

17

(Gains)/losses on securities

(100)

(68)

Orthopaedics Separation related

48

—

COVID-19 Vaccine related costs

—

23

Medical Device Regulation

—

47

Other

(9)

—

Tax Adjustments

Tax impact on special item adjustments 2

(445)

(80)

Tax legislation and other tax related

(742)

61

Adjusted Net Earnings, after tax

$6,009

$4,946

Average shares outstanding (Diluted)

2,439.0

2,427.1

Adjusted net earnings per share (Diluted)

$2.46

$2.04

Operational adjusted net earnings per share (Diluted)

$2.35

Notes:

1In fiscal 2023, the company completed a prioritization of its research and development (R&D) investment within the Innovative Medicine segment to focus on the most promising medicines with the greatest benefit to patients. This resulted in the exit of certain programs within therapeutic areas. The R&D program exits were primarily in infectious diseases and vaccines including the discontinuation of its respiratory syncytial virus (RSV) adult vaccine program, hepatitis and HIV development. The restructuring expense of $102 million in fiscal 2024 included the termination of partnered and non-partnered program costs, asset impairments and asset divestments. This program was completed in Q4 2024.

In fiscal 2023, the company initiated a restructuring program of its Orthopaedics franchise within the MedTech segment to streamline operations by exiting certain markets, product lines and distribution network arrangements. The restructuring expense of $162 million in the fiscal fourth quarter of 2025 ($307 million Q4 2025 YTD) and $60 million in the fiscal fourth quarter of 2024 ($167 million Q4 2024 YTD) primarily includes costs related to market and product exits. This program was substantially completed in Q4 2025.

In fiscal 2025, the company initiated a restructuring program of its Surgery franchise within the MedTech segment to simplify and focus operations by exiting certain non-strategic product lines and optimize select sites across the network. The restructuring expense of $48 million in the fiscal fourth quarter of 2025 ($205 million Q4 2025 YTD) primarily includes costs related to asset impairments and market and product exits. This program is expected to be substantially completed by the end of fiscal year 2026.

2The tax impact related to special item adjustments reflects the current and deferred income taxes associated with the above pre-tax special items in arriving at adjusted earnings.

Johnson & Johnson and subsidiaries

Reconciliation of non-GAAP financial measures

Twelve Months Ended

(Dollars in Millions Except Per Share Data)

2025

2024

Net Earnings, after tax- as reported

$26,804

$14,066

Pre-tax Adjustments

Litigation related

(6,040)

5,450

Intangible Asset Amortization expense

4,621

4,526

Restructuring related 1

512

269

Acquisition, integration and divestiture related

285

1,226

IPR&D impairments

81

211

(Gains)/losses on securities

(427)

306

Orthopaedics Separation related

48

—

COVID-19 Vaccine related costs

—

100

Medical Device Regulation

—

204

Other

20

—

Tax Adjustments

Tax impact on special item adjustments 2

381

(2,135)

Tax legislation and other tax related

(70)

19

Adjusted Net Earnings, after tax

$26,215

$24,242

Average shares outstanding (Diluted)

2,429.4

2,429.4

Adjusted net earnings per share (Diluted)

$10.79

$9.98

Operational adjusted net earnings per share (Diluted)

$10.58

Notes:

1In fiscal 2023, the company completed a prioritization of its research and development (R&D) investment within the Innovative Medicine segment to focus on the most promising medicines with the greatest benefit to patients. This resulted in the exit of certain programs within therapeutic areas. The R&D program exits were primarily in infectious diseases and vaccines including the discontinuation of its respiratory syncytial virus (RSV) adult vaccine program, hepatitis and HIV development. The restructuring expense of $102 million in fiscal 2024 included the termination of partnered and non-partnered program costs, asset impairments and asset divestments. This program was completed in Q4 2024.

In fiscal 2023, the company initiated a restructuring program of its Orthopaedics franchise within the MedTech segment to streamline operations by exiting certain markets, product lines and distribution network arrangements. The restructuring expense of $162 million in the fiscal fourth quarter of 2025 ($307 million Q4 2025 YTD) and $60 million in the fiscal fourth quarter of 2024 ($167 million Q4 2024 YTD) primarily includes costs related to market and product exits. This program was substantially completed in Q4 2025.

In fiscal 2025, the company initiated a restructuring program of its Surgery franchise within the MedTech segment to simplify and focus operations by exiting certain non-strategic product lines and optimize select sites across the network. The restructuring expense of $48 million in the fiscal fourth quarter of 2025 ($205 million Q4 2025 YTD) primarily includes costs related to asset impairments and market and product exits. This program is expected to be substantially completed by the end of fiscal year 2026.

2The tax impact related to special item adjustments reflects the current and deferred income taxes associated with the above pre-tax special items in arriving at adjusted earnings.

Johnson & Johnson and subsidiaries

Reconciliation of non-GAAP financial measures

Adjusted operational sales growth(A)

Fourth quarter 2025 actual vs. 2024 actual

Segments

Innovative Medicine

MedTech

Total

WW As Reported

10.0

%

7.5

%

9.1

%

U.S.

7.9

%

6.6

%

7.5

%

International

13.4

%

8.5

%

11.3

%

WW Currency

2.1

1.7

2.0

U.S.

—

—

—

International

5.5

3.6

4.7

WW Operational

7.9

%

5.8

%

7.1

%

U.S.

7.9

%

6.6

%

7.5

%

International

7.9

%

4.9

%

6.6

%

Caplyta

(1.7)

(1.1)

U.S.

(2.8)

(1.9)

International

0.0

0.0

All Other Acquisitions and Divestitures (A&D)

0.0

0.1

0.1

U.S.

0.0

0.1

0.1

International

0.1

0.2

0.2

WW Adjusted Operational Ex A&D

6.2

%

5.9

%

6.1

%

U.S.

5.1

%

6.7

%

5.7

%

International

8.0

%

5.1

%

6.8

%

Note: Percentages are based on actual, non-rounded figures and may not sum

(A) NON-GAAP FINANCIAL MEASURE “Adjusted operational sales growth" excludes acquisitions, divestitures and translational currency and is a non-GAAP financial measure. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP. Due to the variable nature of acquisitions and divestitures, and the impact they may have on the analysis of underlying business performance and trends, management believes that providing this measure enhances an investor’s understanding of the Company’s performance and may assist in the evaluation of ongoing business operations period over period. This non-GAAP financial measure is presented to permit investors to more fully understand how management assesses the performance of the Company, including for internal evaluation of the performance of the Company's businesses and planning and forecasting for future periods.

The use of this non-GAAP financial measure as a performance measure is limited in that it provides a view of the Company's results of operations without including all events during a period and may not provide a comparable view of the Company's performance to that of other companies in the health care industry.

Johnson & Johnson and subsidiaries

Reconciliation of non-GAAP financial measures

Adjusted operational sales growth(A)

Twelve months 2025 actual vs. 2024 actual

Segments

Innovative Medicine

MedTech

Total

WW As Reported

6.0

%

6.1

%

6.0

%

U.S.

7.0

%

6.6

%

6.9

%

International

4.6

%

5.5

%

5.0

%

WW Currency

0.7

0.7

0.7

U.S.

—

—

—

International

1.7

1.4

1.6

WW Operational

5.3

%

5.4

%

5.3

%

U.S.

7.0

%

6.6

%

6.9

%

International

2.9

%

4.1

%

3.4

%

Shockwave

(1.4)

(0.5)

U.S.

(2.1)

(0.7)

International

(0.5)

(0.2)

Caplyta

(1.2)

(0.7)

U.S.

(2.1)

(1.4)

International

0.0

0.0

All Other Acquisitions and Divestitures (A&D)

0.0

0.3

0.1

U.S.

0.0

0.3

0.1

International

0.1

0.2

0.1

WW Adjusted Operational Ex A&D

4.1

%

4.3

%

4.2

%

U.S.

4.9

%

4.8

%

4.9

%

International

3.0

%

3.8

%

3.3

%

Note: Percentages are based on actual, non-rounded figures and may not sum

(A) NON-GAAP FINANCIAL MEASURE “Adjusted operational sales growth" excludes acquisitions, divestitures and translational currency and is a non-GAAP financial measure. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP. Due to the variable nature of acquisitions and divestitures, and the impact they may have on the analysis of underlying business performance and trends, management believes that providing this measure enhances an investor’s understanding of the Company’s performance and may assist in the evaluation of ongoing business operations period over period. This non-GAAP financial measure is presented to permit investors to more fully understand how management assesses the performance of the Company, including for internal evaluation of the performance of the Company's businesses and planning and forecasting for future periods.

The use of this non-GAAP financial measure as a performance measure is limited in that it provides a view of the Company's results of operations without including all events during a period and may not provide a comparable view of the Company's performance to that of other companies in the health care industry.

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)

ONCOLOGY

US

$3,793

3,019

25.6

%

25.6

%

—

%

Intl

3,069

2,476

23.9

17.3

6.6

WW

6,861

5,497

24.8

21.9

2.9

CARVYKTI

US

420

304

38.2

38.2

—

Intl

135

31

*

*

*

WW

555

334

65.8

63.2

2.6

DARZALEX

US

2,332

1,799

29.6

29.6

—

Intl

1,571

1,285

22.3

16.2

6.1

WW

3,903

3,084

26.6

24.1

2.5

ERLEADA

US

405

342

18.6

18.6

—

Intl

554

442

25.3

17.5

7.8

WW

959

784

22.4

18.0

4.4

IMBRUVICA

US

207

250

(17.4)

(17.4)

—

Intl

478

481

(0.8)

(7.5)

6.7

WW

684

731

(6.5)

(10.9)

4.4

RYBREVANT / LAZCLUZE(3)

US

146

101

45.6

45.6

—

Intl

70

21

*

*

*

WW

216

122

78.0

76.5

1.5

TALVEY

US

105

68

53.8

53.8

—

Intl

44

17

*

*

*

WW

149

85

75.8

73.1

2.7

TECVAYLI

US

110

108

2.7

2.7

—

Intl

66

38

72.2

65.1

7.1

WW

176

146

20.8

18.9

1.9

ZYTIGA / abiraterone acetate

US

5

9

(41.4)

(41.4)

—

Intl

115

127

(9.9)

(11.1)

1.2

WW

119

135

(11.9)

(13.0)

1.1

OTHER ONCOLOGY

US

61

39

54.8

54.8

—

Intl

39

36

8.4

3.0

5.4

WW

100

75

32.9

30.3

2.6

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

IMMUNOLOGY

US

$2,495

2,856

(12.6)

%

(12.6)

%

—

%

Intl

1,364

1,383

(1.4)

(5.5)

4.1

WW

3,860

4,238

(8.9)

(10.3)

1.4

REMICADE

US

248

231

7.1

7.1

—

US Exports(4)

11

9

17.1

17.1

—

Intl

110

117

(5.6)

(7.3)

1.7

WW

370

359

3.2

2.6

0.6

SIMPONI / SIMPONI ARIA

US

287

262

9.6

9.6

—

Intl

345

321

7.4

3.7

3.7

WW

632

583

8.4

6.4

2.0

STELARA

US

766

1,699

(54.9)

(54.9)

—

Intl

462

650

(28.8)

(32.3)

3.5

WW

1,230

2,349

(47.7)

(48.6)

0.9

TREMFYA

US

1,145

654

75.1

75.1

—

Intl

445

295

50.9

44.0

6.9

WW

1,589

949

67.6

65.4

2.2

OTHER IMMUNOLOGY

US

39

0

*

*

—

Intl

2

0

*

*

*

WW

40

0

*

*

*

NEUROSCIENCE

US

1,439

1,148

25.4

25.4

—

Intl

675

628

7.6

4.3

3.3

WW

2,115

1,775

19.1

17.9

1.2

CAPLYTA(5)

US

249

—

*

*

—

Intl

—

—

—

—

—

WW

249

—

*

*

—

CONCERTA / methylphenidate

US

6

33

(79.6)

(79.6)

—

Intl

126

125

(0.3)

(1.4)

1.1

WW

132

159

(17.1)

(17.8)

0.7

INVEGA SUSTENNA / XEPLION / INVEGA

TRINZA / TREVICTA

US

704

796

(11.5)

(11.5)

—

Intl

281

267

5.2

1.9

3.3

WW

986

1,063

(7.3)

(8.2)

0.9

SPRAVATO

US

438

269

63.0

63.0

—

Intl

64

28

*

*

*

WW

503

297

69.0

67.8

1.2

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

OTHER NEUROSCIENCE

US

$

40

49

(18.3)

%

(18.3)

%

—

%

Intl

205

206

(0.7)

(4.3)

3.6

WW

245

255

(4.1)

(6.9)

2.8

PULMONARY HYPERTENSION

US

865

819

5.7

5.7

—

Intl

319

274

16.4

12.2

4.2

WW

1,184

1,092

8.4

7.4

1.0

OPSUMIT / OPSYNVI

US

458

408

11.9

11.9

—

Intl

185

162

14.8

10.9

3.9

WW

643

570

12.7

11.6

1.1

UPTRAVI

US

397

391

1.6

1.6

—

Intl

94

75

26.9

20.8

6.1

WW

491

465

5.7

4.7

1.0

OTHER PULMONARY HYPERTENSION

US

10

19

(43.7)

(43.7)

—

Intl

39

38

2.6

1.2

1.4

WW

49

57

(12.5)

(13.5)

1.0

INFECTIOUS DISEASES

US

303

331

(8.5)

(8.5)

—

Intl

505

443

13.9

5.6

8.3

WW

807

774

4.3

(0.4)

4.7

EDURANT / rilpivirine

US

5

7

(39.1)

(39.1)

—

Intl

379

315

20.6

11.1

9.5

WW

383

322

19.2

9.9

9.3

PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA

US

294

321

(8.4)

(8.4)

—

Intl

89

86

3.6

(2.9)

6.5

WW

383

407

(5.8)

(7.2)

1.4

OTHER INFECTIOUS DISEASES

US

4

1

92.9

92.9

—

Intl

37

43

(14.5)

(18.0)

3.5

WW

40

45

(9.9)

(13.2)

3.3

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

CARDIOVASCULAR / METABOLISM / OTHER

US

$

794

805

(1.4)

%

(1.4)

%

—

%

Intl

142

153

(6.3)

(10.7)

4.4

WW

936

957

(2.2)

(2.9)

0.7

XARELTO

US

687

676

1.7

1.7

—

Intl

—

—

—

—

—

WW

687

676

1.7

1.7

—

OTHER

US

107

130

(17.4)

(17.4)

—

Intl

142

153

(6.3)

(10.7)

4.4

WW

249

281

(11.4)

(13.8)

2.4

TOTAL INNOVATIVE MEDICINE

US

9,689

8,977

7.9

7.9

—

Intl

6,074

5,355

13.4

7.9

5.5

WW

$

15,763

14,332

10.0

%

7.9

%

2.1

%

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

MEDTECH SEGMENT(2)

CARDIOVASCULAR

US

$

1,374

1,221

12.5

%

12.5

%

—

%

Intl

925

841

10.1

6.8

3.3

WW

2,299

2,062

11.5

10.1

1.4

ELECTROPHYSIOLOGY

US

746

681

9.5

9.5

—

Intl

679

640

6.2

3.2

3.0

WW

1,425

1,321

7.9

6.5

1.4

ABIOMED

US

358

308

16.5

16.5

—

Intl

102

77

33.1

25.4

7.7

WW

460

384

19.8

18.3

1.5

SHOCKWAVE

US

238

202

18.0

18.0

—

Intl

80

56

42.3

40.7

1.6

WW

318

258

23.3

22.9

0.4

OTHER CARDIOVASCULAR

US

31

31

(0.1)

(0.1)

—

Intl

64

68

(6.7)

(8.8)

2.1

WW

95

99

(4.6)

(6.1)

1.5

ORTHOPAEDICS

US

1,520

1,460

4.2

4.2

—

Intl

918

856

7.3

2.3

5.0

WW

2,438

2,315

5.3

3.5

1.8

HIPS

US

284

272

4.3

4.3

—

Intl

154

146

5.5

0.4

5.1

WW

439

418

4.7

2.9

1.8

KNEES

US

251

238

5.1

5.1

—

Intl

181

160

13.7

9.2

4.5

WW

432

398

8.6

6.8

1.8

TRAUMA

US

543

514

5.6

5.6

—

Intl

270

250

7.9

2.7

5.2

WW

813

764

6.4

4.7

1.7

SPINE, SPORTS & OTHER

US

442

434

1.9

1.9

—

Intl

312

300

4.2

(0.7)

4.9

WW

756

735

2.8

0.8

2.0

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

FOURTH QUARTER

% Change

2025

2024

Reported

Operational(1)

Currency

MEDTECH SEGMENT(2)(Continued)

SURGERY

US

$1,081

1,038

4.2

%

4.2

%

—

%

Intl

1,563

1,469

6.4

3.4

3.0

WW

2,644

2,507

5.5

3.7

1.8

ADVANCED

US

489

478

2.5

2.5

—

Intl

687

673

1.9

(0.8)

2.7

WW

1,175

1,151

2.2

0.6

1.6

GENERAL

US

592

560

5.6

5.6

—

Intl

876

795

10.2

6.9

3.3

WW

1,468

1,357

8.3

6.3

2.0

VISION

US

531

509

4.3

4.3

—

Intl

889

794

11.9

8.5

3.4

WW

1,420

1,303

8.9

6.8

2.1

CONTACT LENSES / OTHER

US

417

396

5.3

5.3

—

Intl

592

541

9.3

5.3

4.0

WW

1,008

937

7.6

5.3

2.3

SURGICAL

US

113

113

0.6

0.6

—

Intl

297

252

17.7

15.3

2.4

WW

411

365

12.4

10.8

1.6

TOTAL MEDTECH

US

4,506

4,227

6.6

6.6

—

Intl

4,295

3,961

8.5

4.9

3.6

WW

$8,801

8,188

7.5

%

5.8

%

1.7

%

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)

ONCOLOGY

US

$13,659

10,854

25.8

%

25.8

%

—

%

Intl

11,721

9,926

18.1

15.6

2.5

WW

25,380

20,781

22.1

20.9

1.2

CARVYKTI

US

1,492

869

71.6

71.6

—

Intl

395

94

*

*

*

WW

1,887

963

95.9

94.3

1.6

DARZALEX

US

8,266

6,588

25.5

25.5

—

Intl

6,085

5,082

19.7

17.5

2.2

WW

14,351

11,670

23.0

22.0

1.0

ERLEADA

US

1,453

1,282

13.4

13.4

—

Intl

2,121

1,717

23.5

20.1

3.4

WW

3,574

2,999

19.2

17.2

2.0

IMBRUVICA

US

892

1,020

(12.5)

(12.5)

—

Intl

1,931

2,018

(4.3)

(6.7)

2.4

WW

2,823

3,038

(7.1)

(8.6)

1.5

RYBREVANT / LAZCLUZE(3)

US

534

257

*

*

—

Intl

200

70

*

*

*

WW

734

327

*

*

*

TALVEY

US

340

241

40.9

40.9

—

Intl

123

46

*

*

*

WW

463

287

61.3

60.3

1.0

TECVAYLI

US

444

418

6.3

6.3

—

Intl

226

131

72.8

70.4

2.4

WW

670

549

22.1

21.5

0.6

ZYTIGA / abiraterone acetate

US

23

34

(33.2)

(33.2)

—

Intl

480

597

(19.7)

(20.5)

0.8

WW

502

631

(20.4)

(21.2)

0.8

OTHER ONCOLOGY

US

214

145

47.5

47.5

—

Intl

162

172

(6.0)

(7.8)

1.8

WW

376

317

18.5

17.5

1.0

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

IMMUNOLOGY

US

$9,872

11,355

(13.1)

%

(13.1)

%

—

%

Intl

5,856

6,473

(9.5)

(10.2)

0.7

WW

15,728

17,828

(11.8)

(12.0)

0.2

REMICADE

US

1,171

1,009

16.0

16.0

—

US Exports(4)

74

98

(24.8)

(24.8)

—

Intl

523

497

5.3

6.2

(0.9)

WW

1,768

1,605

10.2

10.5

(0.3)

SIMPONI / SIMPONI ARIA

US

1,193

1,082

10.3

10.3

—

Intl

1,475

1,108

33.1

32.8

0.3

WW

2,668

2,190

21.8

21.7

0.1

STELARA

US

3,847

6,720

(42.7)

(42.7)

—

Intl

2,230

3,641

(38.7)

(39.3)

0.6

WW

6,078

10,361

(41.3)

(41.5)

0.2

TREMFYA

US

3,529

2,443

44.5

44.5

—

Intl

1,626

1,227

32.5

30.4

2.1

WW

5,155

3,670

40.5

39.8

0.7

OTHER IMMUNOLOGY

US

59

3

*

*

—

Intl

2

0

*

*

*

WW

61

3

*

*

*

NEUROSCIENCE

US

5,151

4,398

17.1

17.1

—

Intl

2,686

2,718

(1.2)

(1.8)

0.6

WW

7,837

7,115

10.1

9.9

0.2

CAPLYTA(5)

US

700

—

*

*

—

Intl

—

—

—

—

—

WW

700

—

*

*

—

CONCERTA / methylphenidate

US

82

134

(38.6)

(38.6)

—

Intl

502

507

(1.2)

(0.7)

(0.5)

WW

584

641

(9.0)

(8.6)

(0.4)

INVEGA SUSTENNA / XEPLION / INVEGA

TRINZA / TREVICTA

US

2,725

3,125

(12.8)

(12.8)

—

Intl

1,085

1,097

(1.1)

(1.8)

0.7

WW

3,810

4,222

(9.8)

(9.9)

0.1

SPRAVATO

US

1,485

929

59.9

59.9

—

Intl

210

148

41.9

39.1

2.8

WW

1,696

1,077

57.4

57.0

0.4

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

OTHER NEUROSCIENCE

US

$

159

210

(24.5)

%

(24.5)

%

—

%

Intl

889

965

(7.9)

(8.7)

0.8

WW

1,048

1,175

(10.9)

(11.5)

0.6

PULMONARY HYPERTENSION

US

3,223

3,143

2.6

2.6

—

Intl

1,214

1,140

6.5

4.9

1.6

WW

4,437

4,282

3.6

3.2

0.4

OPSUMIT / OPSYNVI

US

1,633

1,557

4.8

4.8

—

Intl

692

668

3.7

2.1

1.6

WW

2,325

2,225

4.5

4.0

0.5

UPTRAVI

US

1,536

1,511

1.7

1.7

—

Intl

366

307

19.4

17.4

2.0

WW

1,902

1,817

4.7

4.3

0.4

OTHER PULMONARY HYPERTENSION

US

54

75

(27.0)

(27.0)

—

Intl

155

165

(6.2)

(6.8)

0.6

WW

209

240

(12.7)

(13.0)

0.3

INFECTIOUS DISEASES

US

1,264

1,354

(6.6)

(6.6)

—

Intl

1,977

2,042

(3.2)

(6.5)

3.3

WW

3,241

3,396

(4.6)

(6.5)

1.9

EDURANT / rilpivirine

US

26

31

(18.4)

(18.4)

—

Intl

1,461

1,241

17.7

13.0

4.7

WW

1,486

1,272

16.9

12.2

4.7

PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA

US

1,226

1,311

(6.5)

(6.5)

—

Intl

353

401

(11.9)

(13.7)

1.8

WW

1,579

1,712

(7.7)

(8.1)

0.4

OTHER INFECTIOUS DISEASES

US

12

11

6.6

6.6

—

Intl

163

401

(59.3)

(59.5)

0.2

WW

175

412

(57.5)

(57.7)

0.2

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

INNOVATIVE MEDICINE SEGMENT(2)(Continued)

CARDIOVASCULAR / METABOLISM / OTHER

US

$

3,175

2,866

10.8

%

10.8

%

—

%

Intl

603

696

(13.3)

(13.8)

0.5

WW

3,778

3,562

6.1

6.0

0.1

XARELTO

US

2,633

2,373

11.0

11.0

—

Intl

—

—

—

—

—

WW

2,633

2,373

11.0

11.0

—

OTHER

US

542

494

9.8

9.8

—

Intl

603

696

(13.3)

(13.8)

0.5

WW

1,145

1,189

(3.7)

(4.0)

0.3

TOTAL INNOVATIVE MEDICINE

US

36,344

33,970

7.0

7.0

—

Intl

24,057

22,994

4.6

2.9

1.7

WW

$

60,401

56,964

6.0

%

5.3

%

0.7

%

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

MEDTECH SEGMENT(2)

CARDIOVASCULAR

US

$

5,305

4,513

17.5

%

17.5

%

—

%

Intl

3,623

3,194

13.4

11.9

1.5

WW

8,928

7,707

15.8

15.2

0.6

ELECTROPHYSIOLOGY

US

2,891

2,738

5.6

5.6

—

Intl

2,743

2,529

8.5

7.3

1.2

WW

5,634

5,267

7.0

6.4

0.6

ABIOMED

US

1,393

1,213

14.9

14.9

—

Intl

358

284

26.4

22.0

4.4

WW

1,751

1,496

17.1

16.2

0.9

SHOCKWAVE

US

897

442

*

*

—

Intl

249

122

*

*

*

WW

1,146

564

*

*

*

OTHER CARDIOVASCULAR

US

124

120

3.1

3.1

—

Intl

273

260

4.9

4.1

0.8

WW

397

380

4.3

3.8

0.5

ORTHOPAEDICS

US

5,720

5,689

0.5

0.5

—

Intl

3,538

3,470

2.0

(0.2)

2.2

WW

9,258

9,158

1.1

0.3

0.8

HIPS

US

1,080

1,057

2.1

2.1

—

Intl

594

581

2.2

0.1

2.1

WW

1,674

1,638

2.1

1.4

0.7

KNEES

US

924

922

0.2

0.2

—

Intl

663

623

6.5

4.6

1.9

WW

1,587

1,545

2.7

2.0

0.7

TRAUMA

US

2,058

2,013

2.2

2.2

—

Intl

1,088

1,036

5.0

2.7

2.3

WW

3,146

3,049

3.2

2.4

0.8

SPINE, SPORTS & OTHER

US

1,658

1,696

(2.2)

(2.2)

—

Intl

1,193

1,230

(3.0)

(5.3)

2.3

WW

2,852

2,926

(2.5)

(3.5)

1.0

See footnotes at end of schedule

Johnson & Johnson

Segment sales

(Dollars in Millions)

TWELVE MONTHS

% Change

2025

2024

Reported

Operational(1)

Currency

MEDTECH SEGMENT(2)(Continued)

SURGERY

US

$4,157

4,003

3.9

%

3.9

%

—

%

Intl

5,980

5,842

2.4

1.5

0.9

WW

10,137

9,845

3.0

2.5

0.5

ADVANCED

US

1,900

1,838

3.4

3.4

—

Intl

2,678

2,650

1.0

0.1

0.9

WW

4,577

4,488

2.0

1.5

0.5

GENERAL

US

2,258

2,165

4.3

4.3

—

Intl

3,302

3,192

3.4

2.7

0.7

WW

5,560

5,358

3.8

3.3

0.5

VISION

US

2,225

2,128

4.6

4.6

—

Intl

3,243

3,018

7.4

5.9

1.5

WW

5,468

5,146

6.3

5.3

1.0

CONTACT LENSES / OTHER

US

1,754

1,684

4.1

4.1

—

Intl

2,157

2,049

5.3

3.2

2.1

WW

3,910

3,733

4.8

3.6

1.2

SURGICAL

US

471

444

6.1

6.1

—

Intl

1,086

969

12.1

11.6

0.5

WW

1,558

1,413

10.2

9.9

0.3

TOTAL MEDTECH

US

17,408

16,332

6.6

6.6

—

Intl

16,384

15,525

5.5

4.1

1.4

WW

$33,792

31,857

6.1

%

5.4

%

0.7

%

Note: Column and rows within tables may not add due to rounding. Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.

* Percentage greater than 100% or not meaningful

(1)Operational growth excludes the effect of translational currency

(2)Unaudited

(3)Includes the sales of RYBREVANT and RYBREVANT + LAZCLUZE

(4)Reported as U.S. sales

(5)Acquired with Intra-Cellular Therapies on April 2, 2025

Mentions · how they’re counted

CategoryUnderlinedWord counterModel’s count
AI

AI, artificial intelligence, generative AI, machine learning, large language model, LLM

000
Layoffs

layoffs, RIF, headcount reduction, workforce optimization, restructuring

18—0
Recession

recession, downturn, contraction, slowdown

000
Tariffs

tariff, trade war, trade barriers, trade restrictions, trade policy

000
Buybacks

share repurchase, buyback program

0—0

Underlines use the same word lists the scores use. AI, recession and tariffs follow Palanor’s word counter, so those counts match it exactly on the same text. Layoffs and buybacks use the terms the model was given. The model’s count is an estimate by meaning, not by string, so it can differ from the underlines.

Not placed in the text

These quotes are stored with a score, but no passage here matches them closely enough to highlight. Rather than point at the wrong passage, they are listed as stored.

Theme · oncology franchise acceleration

“DARZALEX US $2,332M +29.6%; CARVYKTI US $420M +38.2%; worldwide oncology $6,861M +24.8%”

Theme · stelara biosimilar impact

“STELARA US $766M (54.9)%; worldwide $1,230M (47.7)%”

Theme · cardiovascular medtech momentum

“SHOCKWAVE WW $318M +23.3%; ABIOMED WW $460M +19.8%; cardiovascular total $2,299M +11.5%”

Theme · neuroscience portfolio expansion

“CAPLYTA US $249M acquired with Intra-Cellular Therapies; SPRAVATO WW $503M +69.0%”

Theme · immunology portfolio transition

“TREMFYA WW $1,589M +67.6%; immunology total WW $3,860M (8.9)%”

Theme · orthopaedics restructuring completion

“restructuring program of Orthopaedics franchise substantially completed in Q4 2025; $162M Q4 expense”

Theme · international operational growth

“International operational sales +6.6%; Europe operational +5.2%; currency benefit +4.7%”

Theme · surgery segment optimization

“Surgery franchise restructuring initiated fiscal 2025; $48M Q4 expense; expected substantially completed end fiscal 2026”

Theme · electrophysiology steady performance

“ELECTROPHYSIOLOGY WW $1,425M +7.9%; US $746M +9.5%”

Theme · vision franchise recovery

“VISION WW $1,420M +8.9%; CONTACT LENSES WW $1,008M +7.6%”

Source: SEC EDGAR · public domain · Highlights by Palanor