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The Largest U.S.-Listed Drugmakers by Revenue
Revenue over the last twelve reported months, $ billions
Plays the chart through its history. Pauses are where a new leader takes first place.
Total revenue from each company’s 10-Q and 10-K filings (SEC XBRL), trailing four quarters; nothing is estimated. Johnson & Johnson (shaded) includes its medical-device business. Foreign drugmakers such as Novo Nordisk, AstraZeneca and Novartis do not file these reports. Each bar is the company’s latest reported quarter.
The size of America’s large drugmakers by what they actually sold, straight from their SEC filings. The ranking moves with launches and patent expiries: the obesity and diabetes drugs have carried Eli Lilly up the list, while companies facing generic competition slip.
What this chart reads·18 series
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- Eli Lilly Revenue, Trailing Twelve Monthsas “Eli Lilly”latest 2026-06-30
- Johnson & Johnson Revenue, Trailing Twelve Monthsas “Johnson & Johnson”latest 2026-06-28
- AbbVie Revenue, Trailing Twelve Monthsas “AbbVie”latest 2026-06-30
- Merck & Co. Revenue, Trailing Twelve Monthsas “Merck”latest 2026-06-30
- Amgen Revenue, Trailing Twelve Monthsas “Amgen”latest 2026-06-30
- Gilead Sciences Revenue, Trailing Twelve Monthsas “Gilead”latest 2026-06-30
- Pfizer Revenue, Trailing Twelve Monthsas “Pfizer”latest 2026-06-28
- Vertex Pharmaceuticals Revenue, Trailing Twelve Monthsas “Vertex”latest 2026-06-30
- Bristol Myers Squibb Revenue, Trailing Twelve Monthsas “Bristol Myers Squibb”latest 2026-06-30
- Moderna Revenue, Trailing Twelve Monthsas “Moderna”latest 2026-06-30
- Regeneron Pharmaceuticals Revenue, Trailing Twelve Monthsas “Regeneron”latest 2026-06-30
- Biogen Revenue, Trailing Twelve Monthsas “Biogen”behindlatest 2026-03-31
- Royalty Pharma Revenue, Trailing Twelve Monthsas “Royalty Pharma”latest 2026-06-30
- Zoetis Revenue, Trailing Twelve Monthsas “Zoetis”latest 2026-06-30
- Alnylam Pharmaceuticals Revenue, Trailing Twelve Monthsas “Alnylam”latest 2026-06-30
- United Therapeutics Revenue, Trailing Twelve Monthsas “United Therapeutics”latest 2026-06-30
- Insmed Revenue, Trailing Twelve Monthsas “Insmed”latest 2026-06-30
- Viatris Revenue, Trailing Twelve Monthsas “Viatris”latest 2026-06-30
Sources·18 sources
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Eli Lilly Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Johnson & Johnson Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
AbbVie Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Merck & Co. Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Amgen Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Gilead Sciences Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Pfizer Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Vertex Pharmaceuticals Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Bristol Myers Squibb Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Moderna Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Regeneron Pharmaceuticals Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Biogen Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Royalty Pharma Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Zoetis Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Alnylam Pharmaceuticals Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
United Therapeutics Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Insmed Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
Viatris Revenue, Trailing Twelve Months. Source: SEC EDGAR XBRL company facts (data.sec.gov), from the company's 10-Q and 10-K filings: us-gaap Revenues, or RevenueFromContractWithCustomerExcludingAssessedTax where that is the tag the company files (the most recently filed revenue tag; older tags fill earlier periods). U.S. government data, public domain. Synced weekly by Palanor's edgar-revenue-sync job. Quarters are derived from the filings' year-to-date figures (the fourth quarter is the annual figure less nine months); twelve-month totals are the sum of four quarters. Calculated by Palanor.
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